A number of beneficial health effects, such as anti-cancer, antiviral, neuroprotective, anti-aging, and anti-inflammatory effects, have been reported in lab tests using the compound RESVERATROL. Resveratrol is found in the skin of red grapes and is a constituent of red wine but, based on extrapolation from animal trials, apparently not in sufficient amounts to explain the “French paradox” that the incidence of coronary heart disease is relatively low in southern France despite high dietary intake of saturated fats.
Biotics Research Corp in conjunction with Mark Houston, M.D. who is Associate Clinical professor of Medicine at Vanderbilt School of Medicine, have developed another Resveratrol-containing product called ResveraSIRT-HP. This new product is a very high potency resveratrol product. Specifically, this products is used to support a healthy vascular system and to promote healthy aging.
Resveratrol is known to stimulate production of a class of enzymes called Sirtuins, labeled in mammals as SIRT-1 through SIRT-7. Sirtuins are known to affect cellular metabolism via selective gene expression, including cell survival, fat metabolism, insulin resistance and generalized cell repair (anti-aging).
In lab testing with various animals Sirtuins play key roles in:
* Gene silencing
* DNA repair
* DNA recombination
* Aging – associated with increased rates of stress-induced
* Cell survival
* Energy metabolism
* Response to stressors
Research on resveratrol has documented improved health and survival of animals on high calorie diets. Caloric restriction in lab animals results in a 50% increase in lifespans. Resveratrol, by stimulating the anti-aging enzymes SIRT-1 through SIRT-3 acts similarly to caloric restriction. Caloric restriction increases mitochondrial functions in humans and animals thereby resulting in increased energy production in the cell.
This compound provides additional antioxidant activity, and has been shown to be very cardio protective and very vascular protective, to inhibit angiogenesis (atherosclerosis) and to down regulate proinflammatory mediators. Resveratrol helps to improve insulin sensitivity and carbohydrate metabolism.
Each capsule of ResveraSIRT-HP supplies 250mg of pure Trans Resveratrol. Quercetin, a bioflavanoid, is added to help slow the metabolism of Resveratrol, since it is metabolized quickly. Also included is IP6 (Calcium Magnesium Phytate), a 6-phosphate ester of Inositol derived from rice. IP6 is also a supporter of the cardiovascular system and aids in the metabolism of insulin. It is used in this supplement for its metal chelating activity to help stabilize the the formula.
As a result of extensive news coverage, sales of resveratrol supplements greatly increased in 2006. There is also concern in the scientific community that many of the currently-available resveratrol supplements contain little or none of the active ingredient. Because of Biotics’ reputation in the healthcare and research community physicians and patients can rest-assured that this is the finest most pure supplement of resveratrol on the market. It had better be because the “real stuff” is expensive.
I looked up the cost of resveratrol in a chemical book I have in my office. Spectrum Chemicals offers pure resveratrol for $35 per 50 mg. That is the pure stuff. Biotics, because they buy resveratrol by the kilogram offers 250mg capsules for a lot less.
**Each capsule contains:
Trans Resveratrol 250mg
IP6 (Calcium Magnesium Phytate 25mg
Ther indredients: Gelatin, water and glycerin.
Recommendation: One (1) capsule one (1) to four (4) times daily as a dietary supplement or as otherwise recommended by your healthcare professional.
Contains: 30 Capsules; 120 Capsules
Product #: 2930; 2931
NDC: 55146-02930; 55146-02931