Leaky Gut Syndrome

When toxic matter and undigested food, collected in the intestines as a result of bowel toxemia, are absorbed from the bowels into the bloodstream, the result is a recognized medical condition known as “leaky gut syndrome.”

The undigested food molecules act as antigens, foreign substances that provoke an immune reaction. Many of these antigens are similar in structure to normal body components, and the antibodies produced to fight them can destroy healthy tissues. Recent studies suggest this immune reaction contributes to, or may cause, rheumatoid arthritis and other degenerative diseases. 1

Bacteria and their toxic by-products can also be absorbed from the bowels into the bloodstream. A deficiency of secretory IgA, an antibody in the colon that binds food and bacterial antigens, can cause an influx of antigens from the bowels into the bloodstream. These antigens can induce autoimmune diseases such as thyroid disease, myasthenia gravis (a disease characterized by great muscular weakness), and some forms of meningitis, according to Patrick Donovan, N.D. 2


Toxins that enter the bloodstream from the colon also burden the liver, circulatory system, lymphatic system, and excretory organs such as the lungs and kidneys. Because the liver plays such a vital role in clearing the blood of toxins, any impairment of liver function may aggravate the damage already done by Bowel toxemia. “Foreign chemicals in the body, whether produced from ingestion or chemical interaction, chemical breakdown, or putrefaction of foodstuff in the fermentive processes, can alter RNA (ribonucleic acid) and DNA (deoxyribonucleic acid),” says Dr. Vargas. “RNA and DNA contain the blueprint for cellular manufacturing and, if tampered with, abnormal cell reproduction can occur. Many scientists believe this provokes cancer and other autoimmune diseases. All these factors make a properly functioning colon imperative to the maintenance of good health.”


1. Rooney, P. J.; Jenkins, R. T.; and Buchanan, W. W. “A Short Review of the Relationship between Intestinal Permeability and INFLAMMATORY Joint Disease.” Clinical and Experimental Rheumatology 8 (1990): 75-83.

Mielants, H.; et al. “Intestinal Mucosal Permeability in INFLAMMATORY Rheumatic Diseases. II. Role of Disease.” Journal of Rheumatology 18 no. 3 (1991): 394-400.

Smith, M. D.; Gibson, R. A.; and Brooks, P. M. “Abnormal BOWEL Permeability in Ankylosing Spondylitis and Rheumatoid Arthritis.” Journal of Rheumatology 12 no. 2 (1985): 299-305.

Lahesmaa-Rantala, R.; et al. “Intestinal Permeability in Patients with Yersinia Triggered Reactive Arthritis.” Annals of the Rheumatic Diseases 50 no. 2 (February 1991): 91-94.

Mielants, H. “Reflections on the Link Between Intestinal Permeability and INFLAMMATORY Joint Disease.” Clinical Experimental Rheumatology 8 no. 5 (Sep-Oct, 1990): 523-524.