Berberine is a bitter-tasting, yellow, plant alkaloid with a long history of medicinal use in Chinese and Ayurvedic medicine. Berberine is present in the roots, rhizomes and stem bark of various plants including goldenseal, goldenthread, oregon grape, barberry, and tree turmeric. Berberine has also been used historically as a dye, due to its yellow color.
Traditional uses are as a traditional medicine or dietary supplement, berberine has shown some activity against fungal infections,ÿCandida albicans, other yeasts, parasites, and bacterial/viral infections. ÿBerberine seems to exert synergistic effects withÿfluconazole (Diflucan) even in drug-resistantÿC. albicansÿinfections.
Some research has been undertaken into possible use againstÿMRSA,ÿ a serious drug resistant infection.
Berberine is considered a natural antibiotic. ÿWhen appliedÿin vitroÿand in combination with methoxyhydnocarpin, an inhibitor of multidrug resistance microorganisms, berberine inhibits growth ofÿStaphylococcus aureus ÿandÿMicrocystis aeruginosa,ÿa toxiccyanobacterium.
Berberine is a component of someÿeye dropÿformulations. There is some evidence it is useful in the treatment ofÿtrachoma, an eye infection, and it has been a standard treatment for leishmaniasis.
Berberine prevents and suppresses proinflammatory cytokines,ÿ and increasesÿadiponectinÿexpressionÿwhich partly explains its versatile health effects. Berberine is a nucleic acid-binding isoquinolone alkaloid with wide potential therapeutic properties.
During the last few decades, many studies have shown berberine has various beneficial effects on the cardiovascular system and significant anti-inflammatory activities.
Berberine exerts up-regulating activity on both the low-density-lipoprotein (LDL) receptors and the insulin receptors. This one-drug-multiple-target characteristic might be suitable for the treatment ofÿmetabolic syndrome.
Berberine integrates insulin signaling with mitochondrial function. This can improve hepatic metabolism during insulin resistance and the metabolic syndrome.
Berberine reduces hepatic fat content in the rats of nonalcoholic fatty liver disease. Berberine also prevents proliferation of hepatic stellate cells, which are central for the development of fibrosis during liver injury. In the 2010 issue of The Journal of Lipid Research scientists showed that Berberine increased the methylation process in the liver that results in reduced liver fat content.
**Each capsule supplies:
Berberine Hydrochloride 500 mg
(from Berberis vulgaris)
Other Ingredients: Cellulose, capsule shell (gelatin and water) and magnesium stearate (vegetable source).
RECOMMENDATION: One (1) capsule each day as a dietary supplement or as otherwise directed by a healthcare professional.
CAUTION: Not recommended for children, pregnant or lactating women.
Contains: 90 Capsules
Product #: 5212